Hair loss
Polynucleotide treatment for hair
A regenerative injectable that supports the follicle environment itself — better hair, not just more of it.
What it is
Polynucleotides are short DNA-derived chains (typically from purified salmon DNA — the same family as Nucleofill for the face) that stimulate skin and follicle regeneration at a cellular level. Used on the scalp, they aim to improve the environment around the follicle: better microcirculation, less inflammation, healthier surrounding tissue.
Where PRP focuses on growth-factor stimulation from your own platelets, polynucleotide treatment is a more general regenerative signal. The two work well together for many clients — and we often plan a combined protocol.
What it treats
- Diffuse thinning where individual hairs are becoming finer (miniaturisation)
- Poor scalp condition — dryness, dullness, sensitivity
- Support alongside other hair-loss treatments (PRP, topical / oral medication)
- Recovery after stressful periods, post-pregnancy shedding, or post-illness hair changes
How it works
- 1 Topical numbing applied to the scalp for 15–20 minutes.
- 2 The polynucleotide solution is injected at multiple small points across the treatment area using a fine needle.
- 3 A starting course is typically three to four sessions, two to four weeks apart.
- 4 Maintenance every 4–6 months keeps the effect compounded.
What to expect
Appointment time
30–45 minutes
Downtime
Mild tenderness and possible small bumps at injection points for 24 hours. Most clients return to normal the same day.
How it feels
Small quick scratches, made comfortable with topical numbing.
Aftercare
No hair washing for 12 hours. Avoid swimming, sauna, or vigorous exercise for 24 hours. Gentle shampoo only for the first few days.
Results visible
Improved hair quality from 4–6 weeks; broader thickening builds over 3 months
How long they last
Sustained with maintenance every 4–6 months
Is this right for you?
A good fit if
- You're addressing early to moderate hair thinning
- You can commit to a starting course of 3–4 sessions
- You want a treatment that complements PRP or topical medication rather than replacing them
Not the right time if
- You have a salmon allergy (polynucleotides are derived from salmon DNA)
- You're pregnant or breastfeeding
- You have an active scalp infection or significant scalp inflammation
Price
From £350 per session · Course of 3 from £950
Final price confirmed in your complimentary consultation. Cancellation policy.
FAQs
How is this different from PRP?
PRP uses your own blood-derived growth factors; polynucleotides use purified salmon DNA-derived molecules. Both are regenerative, both work — they target slightly different mechanisms. Many clients use them together for better outcomes than either alone.
Salmon DNA — is that safe?
Yes — polynucleotides used in clinic are purified to pharmaceutical-grade standards. The molecule used is the same regardless of source. We do not treat clients with confirmed salmon allergy.
How quickly will I see results?
Improved hair quality is often noticeable from 4–6 weeks. Visible thickening builds over 3 months as the follicle environment improves.
Can I keep using topical minoxidil or oral finasteride alongside?
Yes — polynucleotide treatment is compatible with both. In fact, the regenerative signal it provides may help your existing treatments work more effectively.
Related treatments
PRP for hair loss
Platelet-Rich Plasma drawn from your own blood — to slow thinning and support regrowth.
Learn more Nucleofill
Polynucleotide injections for regeneration, texture and the under-eye.
Learn more Mesotherapy
A cocktail of vitamins, hyaluronic acid and antioxidants delivered into the skin.
Learn moreReady when you are
Start with a complimentary consultation.
Thirty minutes, in person, at our Knightsbridge clinic. We'll listen, look, and tell you honestly what we'd recommend — and what we wouldn't.