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Body · Medically-supervised weight loss

Wegovy (semaglutide)

A once-weekly prescription injection, dispensed by GPhC-registered pharmacy, supervised monthly.

Wegovy injection pen and packaging

What it is

Wegovy is the brand name for semaglutide, a once-weekly prescription injection licensed for chronic weight management in adults with obesity or excess weight with at least one weight-related health condition. It acts on the GLP-1 receptor to reduce appetite and slow gastric emptying.

Wegovy has been in use for weight management since 2021 and has a substantial real-world evidence base. In clinical trials (STEP-1), participants on the maintenance dose lost on average around 15% of their baseline body weight at 68 weeks.

What it treats

  • Adults with a BMI ≥ 30
  • Adults with a BMI ≥ 27 plus a weight-related health condition

How it works

  1. 1 Initial consultation with our prescriber.
  2. 2 If eligible, a starting dose of 0.25 mg once weekly is prescribed.
  3. 3 Dose titrates upward monthly — 0.5 mg, 1 mg, 1.7 mg, 2.4 mg — as tolerated.
  4. 4 Monthly review appointments.
  5. 5 Dispensed in a multi-dose pen by our partnered GPhC-registered pharmacy.

What to expect

Appointment time

Self-administered weekly injection at home. Monthly clinic review.

Downtime

None medically. First 2–3 weeks of each new dose may include nausea or reduced appetite.

How it feels

A small subcutaneous needle. Quick prick.

Aftercare

Inject the same day each week, vary site. Avoid heavy or fatty meals in the 24 hours after injection.

Results visible

From week 1–2 (appetite); month 2+ (visible weight loss)

How long they last

Ongoing while medication is appropriate

Is this right for you?

A good fit if

  • You meet the prescribing criteria
  • You're prepared to combine with diet and lifestyle changes
  • You can commit to monthly review

Not the right time if

  • You're pregnant, breastfeeding or planning to become pregnant
  • You have a personal or family history of medullary thyroid cancer or MEN2
  • You have a history of pancreatitis

Price

From £190 per month at the starting dose. Cost increases with dose.

Final price confirmed in your complimentary consultation. Cancellation policy.

FAQs

How does Wegovy compare to Mounjaro?

Mounjaro acts on two receptor pathways (GLP-1 and GIP) and has stronger weight-loss data in head-to-head trials. Wegovy has a longer track record in real-world use. Our prescriber will discuss which suits you.

How much weight will I lose?

Average results in trials are around 15% of body weight at 68 weeks on the maintenance dose. Real-world results vary widely depending on adherence and lifestyle.

Side effects?

Nausea, reduced appetite, constipation or loose stools, fatigue — most common in the first 2–3 weeks of any new dose, settle for most clients.

Is Wegovy available on the NHS?

In some circumstances, through specialist weight-management services. Most clients we see have either not met the NHS criteria, are on a long waiting list, or have chosen private supervision for the speed and convenience.

Ready when you are

Start with a complimentary consultation.

Thirty minutes, in person, at Knightsbridge or Harley Street. We'll listen, look, and tell you honestly what we'd recommend — and what we wouldn't.

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